Description(s):

The pCMV-EGFR (T790M C797S  Exon 19 Deletion) vector contains the EGFR gene with the T790M, C797S, and Exon 19 Deletion mutations under the CMV promoter for high expression in mammalian cell lines such as the HEK 293 cell line. This includes the hygromycin resistant gene embedded in the vector for stable cell line establishment. Downstream of the EGFR viii gene is a DYKDDDDK-tag for Western blotting.

Epidermal growth factor receptor (EGFR) is a transmembrane tyrosine kinase receptor that plays a critical role in regulating cell division and death. 

We offer a collection of unique cloning and expression cDNA vectors contain WT and mutated EGFR gene. These mutations are clinically approved and are under further investigation by many researchers. Our high quality vectors are fully sequenced and are ready to use. We also offer custom cloning services for your specific construct needs.