Gene function analysis, target discovery and validation, assay development, and compound screening often need cell-based assays.  Stable cell lines that are engineered to express a gene of interest via transgene integrations into the host genome provide an efficient approach to conduct such analysis.  At Signosis, we help researchers save time and labor in generating and validating stable cell lines so scientists can spend more effort on solving the big questions.  We offer a wide selection of validated luciferase reporter cell lines that measure transcription factor activity as a read-out for various signaling pathways.

Benefits:
  • Routine mycoplasma testing - All cell lines tested negative for mycoplasma.
  • High sensitivity and responsiveness - Each cell line is validated to induce a strong reporter signal in response to stimuli.
  • Consistent - TF reporter construct is stably integrated into the genome to avoid experimental/cell-to-cell variations.
  • Time-saving - Cell line can be used for experiments right away to study different signaling pathways.

  • Firefly Luciferase Substrate -  Click here to learn more about Signosis luciferase substrate.
Product Name Catalog # Price (FP)* Catalog # Price (NP)**   Qty
NFkB Luciferase Reporter HeLa Stable Cell Line SL-0001-FP $2,904 SL-0001-NP $1,671
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Estrogen Receptor Luciferase Reporter T47D Stable Cell Line SL-0002-FP $2,904 SL-0002-NP $1,671
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Stat1 Luciferase Reporter HeLa Stable Cell Line SL-0004-FP $2,904 SL-0004-NP $1,671
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p53 Luciferase Reporter RKO Stable Cell Line SL-0007-FP $3,870 SL-0007-NP $1,973
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AR Luciferase Reporter MDA-MB-453 Stable Cell Line SL-0008-FP $3,870 SL-0008-NP $1,973
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HIF Luciferase Reporter NIH3T3 Stable Cell Line SL-0005-FP $2,904 SL-0005-NP $1,671
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GR Luciferase Reporter MDA-MB-453 Stable Cell Line SL-0009-FP $3,870 SL-0009-NP $1,973
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NFkB Luciferase Reporter NIH 3T3 Stable Cell Line SL-0006-FP $2,904 SL-0006-NP $1,671
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NRF2/ARE Luciferase Reporter MCF7 Stable Cell Line SL-0010-NP $1,973
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p53 Luciferase Reporter HeLa Stable Cell Line SL-0011-FP $3,870 SL-0011-NP $1,973
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NFkB Luciferase Reporter HEK293 Stable Cell Line SL-0012-FP $2,904 SL-0012-NP $1,671
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NFkB Luciferase Reporter MCF7 Stable Cell Line SL-0013-FP $3,870 SL-0013-NP $1,973
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NFkB Luciferase Reporter A549 Stable Cell Line SL-0014-FP $2,904 SL-0014-NP $1,671
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TCF/LEF Luciferase Reporter HEK293 Stable Cell Line SL-0015-FP $3,870 SL-0015-NP $1,973
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SMAD/TGFbeta Luciferase Reporter HepG2 Stable Cell Line SL-0016-FP $3,870 SL-0016-NP $1,973
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NFkB Luciferase Reporter HepG2 Stable Cell Line SL-0017-FP $2,904 SL-0017-NP $1,671
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NFAT Luciferase Reporter HeLa Stable Cell Line SL-0018-FP $2,904 SL-0018-NP $1,671
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AP-1 Luciferase Reporter HeLa Stable Cell Line SL-0019-FP $2,904 SL-0019-NP $1,671
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CREB Luciferase Reporter HEK293 Stable Cell Line SL-0020-FP $2,904 SL-0020-NP $1,671
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GR Luciferase Reporter HeLa Stable Cell Line SL-0021-FP $3,870 SL-0021-NP $1,973
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TCF/LEF Luciferase Reporter HeLa Stable Cell Line SL-0022-FP $2,904 SL-0022-NP $1,671
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HIF Luciferase Reporter HeLa Stable Cell Line SL-0023-FP $2,904 SL-0023-NP $1,671
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ATF6 Luciferase Reporter CHO-K1 Stable Cell Line SL-0024-FP $2,904 SL-0024-NP $1,671
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CHOP Luciferase Reporter Mia-Paca2 Stable Cell Line SL-0025-FP $2,904 SL-0025-NP $1,671
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NFkB Luciferase Reporter Neuro2a Stable Cell Line SL-0026-FP $2,904 SL-0026-NP $1,671
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HIF Luciferase Reporter Neuro2a Stable Cell Line SL-0027-FP $2,904 SL-0027-NP $1,671
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TCF/LEF Luciferase Reporter CHO-K1 Stable Cell Line SL-0028-FP $2,904 SL-0028-NP $1,671
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NFAT Luciferase Reporter NIH 3T3 Stable Cell Line SL-0029-FP $2,904 SL-0029-NP $1,671
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SMAD/TGFbeta Luciferase Reporter NIH/3T3 Stable Cell Line SL-0030-FP $2,904 SL-0030-NP $1,671
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CREB Luciferase Reporter NIH 3T3 Stable Cell Line SL-0031-FP $2,904 SL-0031-NP $1,671
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NFAT Luciferase Reporter Jurkat Stable Cell Line SL-0032-FP $2,904 SL-0032-NP $1,671
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NFkB Luciferase Reporter MEF Stable Cell Line SL-0033-FP $2,904 SL-0033-NP $1,671
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HIF Luciferase Reporter Cos-7 Stable Cell Line SL-0034-FP $2,904 SL-0034-NP $1,671
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IRF Luciferase Reporter HEK293 Stable Cell Line SL-0035-FP $2,904 SL-0035-NP $1,671
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Control HeLa Luciferase Reporter Stable Cell Line SL-0038-FP $1,165 SL-0038-NP $1,165
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Control HepG2 Luciferase Reporter Stable Cell Line SL-0039-FP $1,165 SL-0039-NP $1,165
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ELK-TAD Luciferase Reporter HEK293 Stable Cell Line SL-0040-FP $2,904 SL-0040-NP $1,671
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ELK-TAD Luciferase Reporter HeLa Stable Cell Line SL-0041-FP $2,904 SL-0041-NP $1,671
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NRF2/ARE Luciferase Reporter HEK293 Stable Cell Line SL-0042-FP $2,904 SL-0042-NP $1,671
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NFkB Luciferase Reporter MDA-MB-231 Stable Cell Line SL-0043-FP $2,904 SL-0043-NP $1,671
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NRF2/ARE Luciferase Reporter HepG2 Stable Cell Line SL-0046-FP $2,904 SL-0046-NP $1,671
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SMAD/BMP Responsive Luciferase Reporter HEK293 Cell Line SL-0051-FP $3,870 SL-0051-NP $1,973
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IFN-a/ISRE Luciferase Reporter HeLa Stable Cell Line SL-0052-FP $2,904 SL-0052-NP $1,671
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MRF Luciferase Reporter HEK293 Stable Cell Line SL-0053-FP $2,904 SL-0053-NP $1,671
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FXR Luciferase Reporter HepG2 Stable Cell Line SL-0055-FP $4,245 SL-0055-NP $1,985
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NFkB Luciferase Reporter AGS Stable Cell Line SL-0059-FP $2,904 SL-0059-NP $1,671
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Metabolic Stress Response Luciferase Reporter MEF Stable Cell Line SL-0065-FP $3,870 SL-0065-NP $1,973
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Metabolic Stress Response Luciferase Reporter HEK293 Stable Cell Line SL-0066-FP $3,870 SL-0066-NP $1,973
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ER Stress Luciferase Reporter MEF Stable Cell Line SL-0067-FP $3,870 SL-0067-NP $1,973
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ER Stress Luciferase Reporter HEK293 Stable Cell Line SL-0068-FP $3,870 SL-0068-NP $1,973
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ER Stress Luciferase Reporter HepG2 Stable Cell Line SL-0069-FP $3,870 SL-0069-NP $1,973
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Stat3 Luciferase Reporter HEK293 Stable Cell Line SL-0071-FP $3,870 SL-0071-NP $1,973
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p53 Luciferase Reporter HCT116 Stable Cell Line SL-0072-FP $3,870 SL-0072-NP $1,973
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GAS/Stat1 Luciferase Reporter HCT116 Stable Cell Line SL-0074-FP $3,870 SL-0074-NP $1,973
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XRE Luciferase Reporter HEK293 Stable Cell Line SL-0075-FP $2,904 SL-0075-NP $1,671
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ELK Luciferase Reporter HEK293 Stable Cell Line SL-0077-FP $2,904 SL-0077-NP $1,671
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NFAT Luciferase Reporter HEK293 Stable Cell Line SL-0078-FP $2,904 SL-0078-NP $1,671
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ATF4 Luciferase Reporter HepG2 Stable Cell Line SL-0079-FP $2,904 SL-0079-NP $1,671
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ATF4 Luciferase Reporter HEK293 Stable Cell Line SL-0080-FP $2,904 SL-0080-NP $1,671
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Stat3 Luciferase Reporter HepG2 Stable Cell Line SL-0081-FP $3,870 SL-0081-NP $1,973
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ATF6 Luciferase Reporter HepG2 Stable Cell Line SL-0082-FP $3,870 SL-0082-NP $1,973
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CHOP Luciferase Reporter HEK293 Stable Cell Line SL-0083-FP $3,870 SL-0083-NP $1,973
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ATF6 Luciferase Reporter HEK293 Stable Cell Line SL-0084-FP $3,870 SL-0084-NP $1,973
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NRF2/ARE Luciferase Reporter NIH3T3 Stable Cell Line SL-0047-FP $2,904 SL-0047-NP $1,671
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IL-6 Responsive Luciferase Reporter HEK293 Cell Line SL-0048-FP $3,870 SL-0048-NP $1,973
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IRF Luciferase Reporter HepG2 Stable Cell Line SL-0049-FP $2,904 SL-0049-NP $1,671
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NFkB Luciferase Reporter Jurkat Stable Cell Line SL-0050-FP $3,870 SL-0050-NP $1,973
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  • * For Profit (FP) price is for non-academic, private companies and institutes
  • ** Non Profit (NP) price is for academic, non profit organizations and institutes